KDM1A and neoplasm: LSD1 mediates tumor immunity through various mechanisms, such as regulating autophagy-related gene expression to mediate tumor-associated autophagy 59, 60, affecting immune checkpoint protein expression 34, 61, upregulating immunosuppressive molecules 62, 63, reducing tumor antigen presentation 36, 37, and interfering with hypoxia-mediated tumor physiology and pathogenesis 64, 65.