OT-1 CD8 T cell transfer successfully suppressed growth of the tumor that lack IFN-γR1 in WT → IFN-γR1flox/flox mice, extending the survival, but not in WT → Tie2CreIFNγR1flox/flox mice without IFN-γR1 expression on endothelial cells (Figure 2E-F). This evidence concerns the gene CD8A and neoplasm.