Furthermore, Mfuzz time-series analysis revealed that cytokines such as Basic fibroblast growth factor (bFGF), Interleukin 13 (IL-13), and Interleukin 1 receptor, type I (IL1R1) that revert towards normal levels after 8 weeks of treatment, suggesting their potential as therapeutic targets for MDD. The gene discussed is IL1R1; the disease is major depressive disorder.