In N-glycans, the mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (MGAT) family of enzymes including MGAT1, MGAT4A, and MGAT5A are upregulated in many cancers, to fuel the loss of contact inhibition, increased cell motility, invasion, and metastasis (42, 233, 238–243). This evidence concerns the gene MGAT1 and cancer.