Additionally, by integrating bioinformatic analysis of FOXN1 gene expression with correlation studies, it has been observed that FOXN1 is typically silent in normal lung tissue yet becomes significantly upregulated during the onset and progression of malignant tumors, we thus assume that FOXN1 may act as an oncogene in the occurrence of LUSC and participate in the process of tumor differentiation and migration. The gene discussed is FOXN1; the disease is neoplasm.