IL1B and Behcet disease: In the jejunal mucosa, compared with the BD group, the mRNA levels of pro-inflammatory cytokines TNF-α and IL-1β in the COS1 and COS2 supplementation groups were decreased, and TNF-α in the COS1 group decreased the most by 79.80% (P < 0.05) (Figures 4A, B).