Determining optimal cutoff values for CRC diagnosis (Figure 3C, Table 4, Figure S1C, and Table S4) revealed values of 38.9 pg/mL for INHBA, 13.15 ng/mL for MMP7, 1.635 ng/mL for PSAT1, 2.601 ng/mL for SLC7A5, 280.7 pg/mL for TGFBI, 2.357 ng/mL for CEA, and 9.571 IU/mL for CA19‐9. Here, PSAT1 is linked to colorectal carcinoma.