KANSL1 and sarcoma: Transcriptome analysis comparing the expression profile of sarcoma with KAT6B/A::KANSL1 fusion versus LG-ESS tumors revealed an upregulation of genes primarily involved in DNA replication, cell cycle regulation, and chromatin modification, and a downregulation of several proteasome subunits in the KAT6B/A::KANSL1 group.