BRD7 and cancer: LP99 is the first identified drug binding to the bromodomains of BRD7 and BRD9 to evict both proteins from acetylated histones.502 The BRD9 selective bromodomains inhibitors, such as BI-7271,BI-7273,BI-9564,503 and I-BRD9,504 significantly inhibit the progression of many cancers.