It has been reported that patients with type 2 diabetes mellitus (T2DM) have more than twice the risk of developing late-onset AD compared with nondiabetic individuals (Zhou et al., 2014) and that 80% of AD patients also exhibit symptoms of T2DM or abnormal glucose and insulin levels (S. Gao et al., 2019). The gene discussed is INS; the disease is type 2 diabetes mellitus.