CD4 and autoimmune uveitis: We have found that Longdan Xiegan Decoction, a traditional Chinese formulation for the treatment of autoimmune uveitis, could exert a specifically inhibitory effect on antigen-specific autoreactive T cells from EAU rats rather than CD4-induced Th17 response in healthy rats [34], indicating that there is no significant difference of disease-related genes in normal tissue after medication intervention.