Future work should also test the cross-reactivity of SARS-CoV-2 N and M protein-specific antibodies among VOCs, as N-targeted antibodies in COVID-19 recovered patients are highly cross-reactive to Beta (B.1.351), Gamma (P.1), Delta (B.1.617.2), and Omicron (B.1.1.529) VOCs [74], suggesting that immunogenic epitopes within the N protein are not under selective pressure. This evidence concerns the gene MYOM2 and COVID-19.