Prior studies that examined nucleocapsid-specific T cell epitopes in donors during active COVID19 and after recovery identified the HLA-B*07:02 restricted epitope, SPRWYFYYL, encoded by the N105-N113 peptide as the most immunodominant SARS-CoV-2 T cell epitope with no mutations observed in VOCs to date. The gene discussed is HLA-B; the disease is COVID-19.