LC3 (r = 0.35, permuted p < 0.001; out-of-sample generalizability of model statistics: r = 0.07, permuted p < 0.001; Figure 4a) was driven by neurodevelopmental symptoms, such as concentration difficulties and inattention, daydreaming, and restlessness (Figure 4b, Supplementary file 1b), which were contrasted to a mix of symptoms characterized by emotion dysregulation. Here, MAP1LC3A is linked to Abnormal emotional state.