Deficiency or dysfunction of vWF, which leads to von Willebranddisease (VWD), is characterized by bleeding symptoms such as frequentnosebleeds, easy bruising, and excessive bleeding from minor injuries.34 Additionally, vWF is implicated in various otherconditions, including thrombosis, stroke, and Heyde’s syndrome.35,36 An enhanced sensitivity to detect the galectin-1-vWF interactionholds great promise for improved diagnostic assays for various diseasesin which vWF plays a crucial role. Here, VWF is linked to von Willebrand disease (hereditary or acquired).