Patients with PE‐EC/CH with PE had higher plasma sFlt‐1 levels (Figure 1A, p<0.05), lower plasma PlGF levels (Figure 1B, p<0.05), higher sFlt‐1/PlGF ratio, and higher plasma PROK1 levels compared with the GH group and CH group (Figure 1C, D, all p <0.05). This evidence concerns the gene PROK1 and cyclic hematopoiesis.