Moreover, several studies have suggested that IL-4 and IL-13 may induce eosinophil-effector functions such as chemotaxis under specific conditions, for example, if eosinophils are obtained from patients with atopic dermatitis or after pretreatment with eosinophil-activating cytokine/chemokines such as IL-5, GM-CSF, or regulated on activation, normal T cell expressed and secreted, which were not examined in this study. Here, IL5 is linked to atopic eczema.