For instance, BUB1B, a crucial serine/threonine kinase in the mitotic checkpoint pathway, acts as an oncogenic role in HCC tumor growth and metastasis via activating mTORC1 and JAK-STAT signaling pathways (Qiu et al., 2020; Hamdy et al., 2023). Here, SOAT1 is linked to hepatocellular carcinoma.