RNA-sequencing analysis in human HCC tissues showed that while KIF20A mRNA is barely expressed in normal liver samples, HCC patients with stage I/II/III have ∼6.08-fold, ∼7.50-fold and ∼8.02-fold higher expression levels of KIF20A (p < 0.0001) (Figure 1D). Here, KIF20A is linked to hepatocellular carcinoma.