The results showed statistically significant differences among the quartile groups (Q1–Q4) in age, PH, PaO2, total CO2, SBP, total bilirubin, potassium, lactate, albumin, PPT, PT, ALT, AST, WBC, heart rate, DBP, temperature, respiratory rate, SOFA score, GCS score, charlson comorbidity index, myocardial infarction, diabetes, CRRT, and 28-day mortality rate. The gene discussed is ALB; the disease is diabetes mellitus.