ZNF165 emerges as a constituent of the Kruppel-like cadre of zinc-finger transcription modulators, notorious for its upregulation across a spectrum of malignancies encompassing urinary bladder transitional cell carcinoma [50], gastrointestinal cancer [51], and hepatocellular carcinoma [52], triple-negative breast cancer [53]. The gene discussed is ZNF165; the disease is bladder transitional cell carcinoma.