Analysis of the top proteins with the most interactions identifies pathways which are also important for disease progression in cancer, such as epidermal growth factor signalling (via EGFR and EGFRpY1173) [35], the MAPK pathway (via p38MAPK and MAPKpT202Y204) [36], and the BCL-regulated apoptotic pathway (via BCL-2 and BCL-xL) [37]. Here, EGF is linked to cancer.