NOTCH1 and central nervous system cancer: NOTCH1 (neurogenic locus notch homolog protein 1) has CLIFI values largely centred around 0 except for brain lower grade gliomas, however while it may appear its expression may not relate to differences between other cancers, its distributions are considerably different from the MTOR (mammalian target of rapamycin) protein which is not associated with any class separation in any model.