CRISP3 and Sepsis: The results indicated that a random-effects model was performed due to an apparent heterogeneity (p < 0.001, I2 = 90%), and a remarkable overexpression of CRISP3 mRNA was observed in the sepsis patients (n = 2,073) compared with the controls (n = 628) [SMD = 0.85 (0.50–1.20), p < 0.001] (Figure 1).