Fan et al. predicted VEGF expression in HCC patients based on MRI imageomics profiles, and multivariate logistic regression analysis showed that AFP, NLR, and irregular lesion boundaries were independent predictors, and AUC of the clinical model and imageomics model in the training and test dataset were 0.709, 0.725; 0.892, 0.800, respectively (44). This evidence concerns the gene AFP and hepatocellular carcinoma.