Therefore, before and after surgery, we need to take a series of targeted preventive and therapeutic measures, such as preoperative assessment of the patient’s dry eye symptoms, optimization of femtosecond laser parameters, anti-inflammatory treatment, targeted supplementation of artificial tears, and promotion of mucin secretion, to reduce the risk of postoperative dry eye and alleviate postoperative dry eye symptoms. This evidence concerns the gene MUC5AC and Keratoconjunctivitis sicca.