Since previous studies have shown that Il‐10−/− mice exhibited obvious lymphatic vessel dysfunction,23, 24 and our previous studies also confirmed that enhanced lymphatic drainage function could relieve colonic inflammation in a sodium trinitrobenzene sulfonate (TNBS)‐induced chronic colitis model,18 we hypothesized that improvement of mesenteric lymphatic function could effectively mitigate intestinal and mesenteric inflammation. The gene discussed is IL10; the disease is colitis.