Interestingly, NEV did not completely block all catalytic sites of the reverse transcriptase enzymes hosted within the CPSF6 condensates, as evidenced by the presence of a residual reverse transcription activity giving rise to a low amount of ERT (early reverse transcripts), detectable by qPCR that did not form LRT (late reverse transcripts) at least within the first 120 h of infection (Fig. 6B). Here, CPSF6 is linked to infection.