However, researchers found that H. pylori infected gastric adenocarcinoma cells AGS increased SLC7A11 expression, while decreased SLC7A11 expression in normal gastric mucosa GES-1 cells, whether this is related to differences between H. pylori strains and host cells, or to other factors is controversial and needs further investigation. The gene discussed is SLC7A11; the disease is gastric adenocarcinoma.