Statistically significant differences were observed in the WT1 mRNA expression levels between the IPSS-R low-risk group(extremely low-risk + low-risk + moderate risk)and the high-risk group(high-risk + extremely high-risk)MDS patients in PB and BM(PB: 2.82±0.89 vs 3.61±0.85, P<0.05; BM: 3.61±0.84 vs 3.92±1.05, P<0.05). The gene discussed is WT1; the disease is myelodysplastic syndrome.