The lack of inflammation or inflammatory damage in the Zika-infected WT mice occurred despite a consistent trend towards increase in splenic weight (S3C Fig), and a trend towards increase in CD3+ T cells and CD11C+ myeloid cells in the testis draining lymph nodes, indicative of peak viral infection at day 7 compared to PBS-injected WT mice (S4 and S5 Figs). This evidence concerns the gene ITGAX and viral infectious disease.