IFNA1 and infection: To further examine the anti-viral potential of IFNɛ against Zika viral infection in the human testis, primary human Sertoli cells were treated with 100 IU rhIFNɛ either 12 hours before infection with 5 or 10 MOI Zika virus to assess a prophylactic effect or 1 hour post-Zika infection to assess a therapeutic effect.