In addition, we found that in glioma, ZNF503-AS2 was significantly associated with LOH (R = 0.29, P < 0.001), MATH (R = -0.35, P < 0.001) and tumor ploidy (R = -0.094, P < 0.05), but not with HRD (ns) (S13C–S13F Fig). Here, ZNF503 is linked to central nervous system cancer.