This transformed the HCPEs into a fluorescent probe fortargeted cellular imaging of HER2-overexpressed cancer cells suchas SKBR-3.369 Zhang and co-workers developedaggregation-induced emission (AIE) active fluorescent polymeric nanoparticles(FPNs) through a catalyst-free thiol–yne click reaction forbioimaging applications. This evidence concerns the gene ERBB2 and cancer.