PDGFRB and breast cancer: Network analysis of KPC cells from Pdgfrb-TK/GCV mice also showed increased activity of signaling pathways involved in metastasis, including “invasion of tumor cell lines,” “invasion of breast cancer cell lines,” “metastasis of tumor cells,” “migration of tumor cells,” “movement of tumor cell lines,” “cell movement of carcinoma cell line,” “invasion of carcinoma cells,” and “transmigration of cells” (Fig. 3C).