Through western blot and qPCR on U87, U251, LN229, SHG44, GSC62, GSC23, HEB and HA1800 cell lines, we confirmed that in these cell lines, COL3A1, GRP65, SRPX2 and GPX8 showed different trends at the gene level between cancer and normal tissues (Figure 4A,B). Here, COL3A1 is linked to cancer.