TLR4 and Mycoplasma pneumoniae pneumonia: During infection with Mycoplasma pneumonia, Staphylococcus aureus, and Pasteurella multicoda DDX5 is degraded, preventing decay of Tlr2 and Tlr4 transcripts and promoting upregulated protein levels of TLR2 and TLR4 critical for induction of antibacterial responses [152].