In the case of DHX15, this interaction augments RIG‐I ATPase activity and enhances IRF3 phosphorylation and IFN induction during influenza B virus (IBV), enterovirus 71(EV71), Sendai virus (SeV), and vesicular stomatitis virus (VSV) infection [51, 52, 69]. The gene discussed is IRF3; the disease is infection.