Consistent with existing data,4 MASH patients with CKD tended to have more severe liver histology than MASH patients with normal renal function at baseline : by using univariate and multivariate analyses (Figure 1d–e, Table 2A) we dissected the effect of GLP-2 response to nutrients from that of baseline liver disease severity and of traditional risk factors for CKD and showed that impaired postprandial GLP-2 response was a distinct feature of renal disease in MASH. The gene discussed is GCG; the disease is chronic kidney disease.