At follow-up data analysis, the changes in postprandial GLP-2 response significantly predicted the presence of CKD and eGFR changes at EOT on univariate and multivariate regression analyses, with the slope of correlation between changes in IAUC GLP-2 and in eGFR overlapping in the two treatment arms (Figure 1h–i, Table 2). This evidence concerns the gene GCG and chronic kidney disease.