DAPK1 and glioblastoma: In addition, curcumin showed the ability of increasing the levels of protein kinase 1 (DAPK1) seizing the G2/M cell cycle in U‐251 cells of malignant GBM, symbolizing the decrease in DAPK1 using curcumin initiate cell arrest and also activates caspase‐3 and seizes NF‐κB and STAT3 (Wu et al., 2013).