This β‐sitosterol nanoformulation ameliorates complete adjuvant‐induced arthritis in rats through nuclear factor‐kappa B (NF‐кB) and heme oxygenase 1/nuclear factor erythroid 2‐related factor 2 (HO‐1/Nrf‐2) pathway (Zhang et al., 2020). Here, HMOX1 is linked to arthritic joint disease.