CD36 and obesity due to melanocortin 4 receptor deficiency: Additionally, studies investigating monolaurate (Zhao et al. 2020) or CO (Borcherding et al. 2022; Lee et al. 2018) showed reduced levels of CD36 in different tissues (Borcherding et al. 2022; Lee et al. 2018; Zhao et al. 2020) either alone or supplemented to an HFD (39%–45%kcal fat) as protective effects against fatty liver (Lee et al. 2018; Zhao et al. 2020) and obesity (Borcherding et al. 2022).