It has been established that L. johnsonii L531 could alleviate Salmonella infantis-associated enteritis and promote intestinal secretory IgA production via regulation of NLRC4 and NLRP3 inflammasomes, NF-κB signaling pathway activation and suppression of mitochondrial damage (Xia et al., 2020). The gene discussed is NLRP3; the disease is enteritis.