In addition, we identified six pleiotropic loci between NAFLD and CAD and identified apolipoprotein C1 (APOC1), translocase of outer mitochondrial membrane 40 (TOMM40) and PBX Homeobox 4 (PBX4) as shared risk genes by MAGMA gene analysis. Here, PBX4 is linked to metabolic dysfunction-associated steatotic liver disease.