GSDMB levels are elevated in inflammatory bowel disease, with GSDMB‐dependent pyroptosis playing a critical role in restoring epithelial barrier function and resolving inflammation304 Additionally, granzyme A (GZMA), traditionally associated with apoptosis, has been found to cleave GSDMB, facilitating tumor clearance when GZMA‐cleavable GSDMB is introduced into mouse cancer cells.305. This evidence concerns the gene GZMA and neoplasm.