Among the specimens of 69 OPSCC patients, 14 exhibited non-keratinizing morphology with p16+ tumor cells comprising more than 70%, and five exhibited keratinizing morphology with p16+ tumor cells comprising more than 70%, whereas the remaining 50 were either p16− or keratinising/non-keratinising morphology with p16+ tumor cells comprising less than 70%. This evidence concerns the gene CDKN2A and neoplasm.