However, adverse reactions to this drug have been observed, including ocular side effects such as uveitis, scleritis, conjunctivitis, and iritis, especially after intravenous administration, which may be mediated by an acute phase reaction associated with interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) [1,2]. The gene discussed is TNF; the disease is conjunctivitis.