HP and cancer: This score's main determinants are platelets < 30,000/uL, presence of hemolysis (reticulocytes >2.5%, total bilirubin >2.0 or decreased haptoglobin), absence of active cancer, absence of stem cell or organ transplant, mean corpuscular volume < 90 fL, INR of <1.5, and Cr of < 2.0 mg/dL [7].