TRIM3 and gastric cancer: Certain circular RNAs (cirRNAs) have the potential to be utilized for early diagnosis.190 By combining various cirRNAs to create a prediction model, it is possible to more accurately distinguish between patients and healthy individuals.191 Moreover, the use of many miRNAs can be employed for the prompt detection of gastric cancer, exhibiting an impressive area under the curve (AUC) value of 0.9299.192 Furthermore, it was discovered that the levels of serum exosomal protein TRIM3 were notably decreased in patients with gastric cancer compared to individuals without the disease.193