Logozzi et al. found that plasma levels of PSA-expressing EVs were higher in PCa patients than in healthy subjects.544 Del Re found that AR-V7 variants in the RNAs of EVs predicted response to ARSI.545 However, another study suggests that EVs may be less predictive than CTCs, which contain a higher amount of AR-V7.546 Overall, further experimental studies are needed for exosome detection in PCa patients. The gene discussed is AR; the disease is posterior cortical atrophy.