CD40LG and obesity due to melanocortin 4 receptor deficiency: There is a marked correlation between the proportion of T-bet + CD11c + B cells in the spleen and serum levels of IgM and IgG2c in both WT and Cd1d1-/- mice, suggesting that the expansion of these B cells and increased antibody production in obesity are supported by iNKT cells, an inflammatory subset capable of producing IFNγ [72].