ASGR1 and cardiovascular disorder: Genome-wide association studies have identified over 200 loci, that influence the risk of atherosclerotic cardiovascular disease [3, 4] and, among them, asialoglycoprotein receptor 1 (ASGR1), the functional subunit of asialoglycoprotein receptor (ASGPR), emerged as a promising candidate affecting plasma cholesterol metabolism and cardiovascular disease (CVD) risk [5].