We observed elevated mRNA levels of B4GALNT1 in tumor tissues from 21 Chinese patients with HCC (p < 0.001) (Fig. 1a), as well as the similar overexpression pattern at mRNA levels in several public HCC datasets, including The Cancer Genome Atlas Liver Hepatocellular Carcinoma (TCGA-LIHC), GSE20140, GSE22058, GSE25097, GSE36376, GSE54236, and GSE76427 (Fig. 1b). Here, B4GALNT1 is linked to hepatocellular carcinoma.