PPP1R13L and acute leukemia: Importantly, the functional role of iASPP in leukemia biology was further confirmed in vivo: NSG mice xenotransplanted with an iASPP-interference MOLM14 leukemia cell model revealed a significantly earlier disease onset, dissemination and progression of acute leukemia of the EV strains as evidenced by phenotype and IVIS Lumina imaging.