In light of our data, it is likely that the SASPs secreted by senescent DPs act in a paracrine manner (Acosta et al., 2013) on the neighboring non‐senescent DPs leading to loss of hair inductivity, and that some of these SASPs may have different effects on other cell types within the HF, such as osteopontin, which induces the hyperproliferation of HF epithelial cells (Wang et al., 2023). This evidence concerns the gene SPP1 and hydrops fetalis.