A few orphan drugs approved in India based on FDA classification are Cannabidiol for the treatment of Lennox-Gastaut syndrome, Pralsetinib for the treatment of adults with metastatic RET fusion-positive non-small cell lung cancer (NSCLC), and Tepotinibe for the treatment of metastatic non-small cell lung cancer with MET exon 14 skipping mutations. Here, RET is linked to Lennox-Gastaut syndrome.